Cardinals D/ST or Colts D/ST: Who Should You Start?
2026 Week 1 · deterministic head-to-head · Verdicts based on PPR scoring.
Colts D/ST beats Cardinals D/ST as the less-bad streaming option this week
Neither unit deserves a lineup spot, but the Colts have the more workable script. Arizona is an 11.5-point road underdog against the Chargers, the kind of spread that tilts games toward garbage time and strips away the sack and takeaway chances a defense needs to score. Indianapolis is only a 3.5-point home dog against Baltimore, a game far more likely to stay competitive into the fourth quarter, and the Ravens are giving the ball away more often than the Chargers are. It's a close call between two units almost nobody starts, decided by game script rather than raw upside.
What flips it: If the Chargers-Cardinals line tightens closer to a competitive spread, Arizona's sack upside could flip this back.
AI editor

Cardinals D/ST
3.43.43.4 Projected Points

Colts D/ST
3.03.03.0 Projected Points
Why Cardinals D/ST
Toss-UpToss-up — a middling defensive matchup (No. 28 this week): LAC gives up 3.8 sacks and 1.2 turnovers a game, and Vegas has them at 28.5 points.
- The Chargers have allowed 3.8 sacks a game, giving Arizona's pass rush more paths to points than Indy's matchup offers.
- At 0% roster share, this defense is purely thin-season filler; only a spike week of takeaways changes that.
Why Colts D/ST
SitSit — a bottom-tier defensive matchup this week (No. 30): Vegas has BAL at 26.5 points, and 3.0 pts projected vs BAL.
- A 3.5-point home spread keeps Indy's defense on the field in a live game instead of chasing points late.
- Baltimore's 1.4 turnovers a game make it the more miscue-prone offense, which matters more than Arizona's sack edge.
Head-to-head stats
| Metric | Cardinals D/ST | Colts D/ST |
|---|---|---|
| Projected points | 3.43.43.4 | 3.03.03.0 |
| Projection rank | Proj.DST28 | Proj.DST30 |
| Started in | 0% of leagues | 1% of leagues |
| Opponent sacks allowed / game | 3.8(2025) | 2.6(2025) |
| Opponent turnovers / game | 1.2(2025) | 1.4(2025) |
| Opponent implied total | 28.5 | 26.5 |
| Home / away | Away | Home |
Signal breakdown
- 3.4 vs 3.0 projected PPR pointsCardinals D/ST +
- Started rank 32 vs 25 (0% vs 1% of leagues)Colts D/ST +
- 3.8 sacks / 1.2 TO vs 2.6 sacks / 1.4 TO per game allowedCardinals D/ST +
- Opponent implied 28.5 vs 26.5 pointsColts D/ST +
- Away vs HomeColts D/ST +
Compare different players
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More D/ST comparisons
- Cardinals D/STCardinals D/STDSTARIvs LAC
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Commanders D/STCommanders D/STDSTWSHvs PHI
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Panthers D/STPanthers D/STDSTCARvs CHI
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Saints D/STSaints D/STDSTNOvs DET
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This week’s toughest calls
- K. WilliamsKyren WilliamsRBLARvs SF
T. Etienne Jr.Travis Etienne Jr.RBNOvs DET
- T. Etienne Jr.Travis Etienne Jr.RBNOvs DET
C. SkatteboCam SkatteboRBNYGvs DAL
- C. SkatteboCam SkatteboRBNYGvs DAL
D. SwiftD'Andre SwiftRBCHIvs CAR
- D. SwiftD'Andre SwiftRBCHIvs CAR
B. TutenBhayshul TutenRBJAXvs CLE
- B. TutenBhayshul TutenRBJAXvs CLE
B. IrvingBucky IrvingRBTBvs CIN
- B. IrvingBucky IrvingRBTBvs CIN
D. MontgomeryDavid MontgomeryRBHOUvs BUF
- T. HigginsTee HigginsWRCINvs TB
D. AdamsDavante AdamsWRLARvs SF
- D. AdamsDavante AdamsWRLARvs SF
D. MooreDJ MooreWRBUFvs HOU
- D. MooreDJ MooreWRBUFvs HOU
J. WilliamsJameson WilliamsWRDETvs NO
- J. WilliamsJameson WilliamsWRDETvs NO
R. OdunzeRome OdunzeWRCHIvs CAR
- R. OdunzeRome OdunzeWRCHIvs CAR
C. SuttonCourtland SuttonWRDENvs KC
- C. SuttonCourtland SuttonWRDENvs KC
C. WatsonChristian WatsonWRGBvs MIN
- K. Pitts Sr.Kyle Pitts Sr.TEATLvs PIT
G. KittleGeorge KittleTESFvs LAR
- G. KittleGeorge KittleTESFvs LAR
S. LaPortaSam LaPortaTEDETvs NO
- S. LaPortaSam LaPortaTEDETvs NO
T. KraftTucker KraftTEGBvs MIN
- T. KraftTucker KraftTEGBvs MIN
T. KelceTravis KelceTEKCvs DEN
- T. KelceTravis KelceTEKCvs DEN
D. GoedertDallas GoedertTEPHIvs WSH
- D. GoedertDallas GoedertTEPHIvs WSH
J. FergusonJake FergusonTEDALvs NYG
- J. HurtsJalen HurtsQBPHIvs WSH
D. PrescottDak PrescottQBDALvs NYG
- D. PrescottDak PrescottQBDALvs NYG
J. DartJaxson DartQBNYGvs DAL
- J. DartJaxson DartQBNYGvs DAL
J. HerbertJustin HerbertQBLACvs ARI
- J. HerbertJustin HerbertQBLACvs ARI
C. WilliamsCaleb WilliamsQBCHIvs CAR
- C. WilliamsCaleb WilliamsQBCHIvs CAR
T. LawrenceTrevor LawrenceQBJAXvs CLE
- T. LawrenceTrevor LawrenceQBJAXvs CLE
B. PurdyBrock PurdyQBSFvs LAR
- C. DickerCameron DickerKLACvs ARI
J. BatesJake BatesKDETvs NO
- J. BatesJake BatesKDETvs NO
T. LoopTyler LoopKBALvs IND
- T. LoopTyler LoopKBALvs IND
H. ButkerHarrison ButkerKKCvs DEN
- H. ButkerHarrison ButkerKKCvs DEN
C. BoswellChris BoswellKPITvs ATL
- C. BoswellChris BoswellKPITvs ATL
E. McPhersonEvan McPhersonKCINvs TB
- E. McPhersonEvan McPhersonKCINvs TB
C. McLaughlinChase McLaughlinKTBvs CIN
- Jaguars D/STJaguars D/STDSTJAXvs CLE
Chargers D/STChargers D/STDSTLACvs ARI
- Chargers D/STChargers D/STDSTLACvs ARI
Titans D/STTitans D/STDSTTENvs NYJ
- Titans D/STTitans D/STDSTTENvs NYJ
Jets D/STJets D/STDSTNYJvs TEN
- Jets D/STJets D/STDSTNYJvs TEN
Eagles D/STEagles D/STDSTPHIvs WSH
- Eagles D/STEagles D/STDSTPHIvs WSH
Bears D/STBears D/STDSTCHIvs CAR
- Bears D/STBears D/STDSTCHIvs CAR
Packers D/STPackers D/STDSTGBvs MIN
- T. Etienne Jr.Travis Etienne Jr.RBNOvs DET
D. AdamsDavante AdamsWRLARvs SF
- D. AdamsDavante AdamsWRLARvs SF
K. WilliamsKyren WilliamsRBLARvs SF
- J. PriceJadarian PriceRBSEAvs NE
T. HigginsTee HigginsWRCINvs TB
- T. HigginsTee HigginsWRCINvs TB
M. LloydMarShawn LloydRBGBvs MIN
- B. IrvingBucky IrvingRBTBvs CIN
R. OdunzeRome OdunzeWRCHIvs CAR
- R. OdunzeRome OdunzeWRCHIvs CAR
B. TutenBhayshul TutenRBJAXvs CLE
- D. SwiftD'Andre SwiftRBCHIvs CAR
J. WilliamsJameson WilliamsWRDETvs NO
- D. MooreDJ MooreWRBUFvs HOU
T. PollardTony PollardRBTENvs NYJ
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