Colts D/ST or 49ers D/ST: Who Should You Start?
2026 Week 1 · deterministic head-to-head · Verdicts based on PPR scoring.
Colts D/ST vs. 49ers D/ST: Two Streaming Afterthoughts, Genuinely Split
Both units sit at the bottom of the weekly rankings, and the tiny separation in points is noise, not signal. The case for Indy is the matchup: Baltimore gives the ball away and gets sacked more than Los Angeles does against San Francisco, and the Colts get to do it at home. The case for San Francisco is thinner opponent giveaways working against them — the Rams protect the football — but the 49ers still carry a touch more lineup share, suggesting the crowd sees a marginally safer floor. Either way this is a streaming decision, not a start, and the model's even call reflects two defenses with almost identical upside ceilings this week.
What flips it: A sudden uptick in Baltimore giveaways or a Rams offensive-line injury report would tip this toward the Colts.
AI editor

Colts D/ST
3.03.03.0 Projected Points

49ers D/ST
2.62.62.6 Projected Points
Why Colts D/ST
SitSit — a bottom-tier defensive matchup this week (No. 30): Vegas has BAL at 26.5 points, and 3.0 pts projected vs BAL.
- Baltimore's 1.4 turnovers and 2.6 sacks allowed per game are the best takeaway equity of this pair.
- Home field nudges the model toward Indy despite almost nobody rostering them (1% of leagues).
Why 49ers D/ST
SitSit — a bottom-tier defensive matchup this week (No. 32): LAR protects the ball (0.9 turnovers a game), and Vegas has them at 25.8 points.
- The Rams protect the ball well (0.9 turnovers/game), which caps San Francisco's ceiling on the road.
- Slightly more trusted by the crowd (4% started vs. 1%), but that's a popularity gap, not a production one.
Head-to-head stats
| Metric | Colts D/ST | 49ers D/ST |
|---|---|---|
| Projected points | 3.03.03.0 | 2.62.62.6 |
| Projection rank | Proj.DST30 | Proj.DST32 |
| Started in | 1% of leagues | 4% of leagues |
| Opponent sacks allowed / game | 2.6(2025) | 1.8(2025) |
| Opponent turnovers / game | 1.4(2025) | 0.9(2025) |
| Opponent implied total | 26.5 | 25.8 |
| Home / away | Home | Away |
Signal breakdown
- 3.0 vs 2.6 projected PPR pointsColts D/ST +
- Started rank 25 vs 20 (1% vs 4% of leagues)49ers D/ST +
- 2.6 sacks / 1.4 TO vs 1.8 sacks / 0.9 TO per game allowedColts D/ST +
- Opponent implied 26.5 vs 25.8 points49ers D/ST +
- Home vs AwayColts D/ST +
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